PA 800 Plus Project Files – Revision History

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Revision A – 20 Jul 2023
- Initial Release
- Total Methods Included:
  - cIEF: 6 methods
  - Fast Glycan: 8 methods
  - IgG: 12 methods
  - Service: 22 methods

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Revision B – 11 Oct 2024
- Enabled full audit trail for all project folders
- Service Project Folder Updates:
  - Renamed “Service” project folder to “Sciex Service”
  - Added new service methods:
    - LIF Test Mix instrument method and method set
    - LIF System Performance report method
    - LIF System Performance sample set
    - UV System Performance sample set
  - Added custom fields to convert:
    - AU → µAU
    - AU/hour → µAU/min
  - Updated report methods:
    - UV Noise and Drift: now displays µAU and µAU/min
    - PDA Noise and Drift: now displays µAU and µAU/min
- Total Methods Included:
  - cIEF: 6 methods
  - Fast Glycan: 8 methods
  - IgG: 12 methods
  - Service: 27 methods

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Revision C – 19 May 2025
- Sciex Service Project Folder Updates:
  - Added new service methods:
    - LIF Rapid Conditioning
    - LIF Shutdown Airdry
    - PDA Rapid Conditioning
    - PDA Shutdown Airdry
    - UV Rapid Conditioning
    - UV Shutdown Airdry
    - LIF Test Mix processing method
    - PDA Noise and Drift sample set
  - Updated UV Test Mix B instrument method: corrected inlet tray type to “48 Vials”
  - Updated report methods: removed irrelevant info from “Sample Information” section
  - Updated sample sets:
    - Removed UV Noise and Drift from UV System Performance Test
    - Removed PDA Noise and Drift from PDA System Performance Test
- Total Methods Included:
  - cIEF: 6 methods
  - Fast Glycan: 8 methods
  - IgG: 12 methods
  - Service: 41 methods

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Revision D – 26 Sep 2025
- cIEF Project Folder:
  - Updated `cIEF_Separation` instrument method: corrected inject event due to known bug
- Sciex Service Project Folder Updates:
  - Updated all report methods:
    - Corrected cutoff fields
    - Added Original Sample Set ID to system info
    - Added System Name to system info
    - Added Result ID, Date Acquired, and Date Processed to peak table
    - Updated header/footer to use Empower default info
  - Added versioning for traceability:
    - Initial methods: no version label
    - Updated methods: labeled V2, V3, V4, etc.
  - Updated UV Test Mix B method set: reflects new instrument method name
  - Updated LIF Rapid Conditioning Instrument method: Changed pressure rinse duration from 20 minutes to 2 minutes
  - Updated LIF Rapid COnditioning method set: reflects new instrument method name
  - Updated LIF Signal to Noise Instrument method: removed temperature monitoring
  - Updated LIF Signal to Noise method set: reflects new instrument method name
  - Updated LIF System Performance sample set: removed LIF Signal to Noise and LIF Rapid Conditioning method set
  - Updated UV System Performance sample set: removed UV Noise and Drift and UV Rapid Conditioning method set
  - Updated PDA System Performance sample set: removed PDA Noise and Drift and PDA Rapid Conditioning method set
  - Added new service methods:
    - LIF Rapid Conditioning Sample Set
    - LIF Shutdown Sample Set
    - UV Rapid Conditioning Sample Set
    - UV Shutdown Sample Set
    - PDA Rapid Conditioning Sample Set
    - PDA Shutdown Sample Set
  - Updated PDA Shutdown Air Dry instrument method: corrected detector type to “PDA”
  - Updated PDA Shutdown Air Dry method set: reflects new instrument method name
- Total Methods Included:
  - cIEF: 6 methods
  - Fast Glycan: 8 methods
  - IgG: 12 methods
  - Service: 47 methods

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Revision E – 10 Jun 2026
- Enabled Full Audit Trail Settings in system policies and created new project folders
  - Set Project Objects: Methods, Results, Sample, Deletion to "Unrestricted"
  - Set Deletion to "Confirm Identity"
- Sciex Service Project Folder Updates:
  - Updated LIF Signal to Noise processing method component from "Time Corrected Area" to "Area"
  - Updated Test Mix B processing method component from "Time Corrected Area" to "Area"